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Drug-Free Relief 

for Vaginal Yeast Infections

Controlled-Cooling Device

Vlisse™ is a prescription, drug-free medical device designed to treat vaginal yeast and bacterial infections using patented controlled-cooling technology. Developed by a board-certified OB/GYN, Vlisse introduces a non-pharmaceutical approach that addresses infection and inflammation without the drugs, hormones, or chemicals commonly used in current treatments.

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VLISSE

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Faster Treatment

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More Effective Treatment

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Immediate Symptom Relief

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Drug Free, No Chemicals

How Vlisse Works!

Four Mechanisms of Action

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*Cures the Infection by returning the hyphae (infection) back to dormant-bud state; kills fungus: confirmed in 2 cases; kills bacteria: confirmed in 4 cases

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Stops inflammation/symptoms of itching, pain, and swelling

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Normalizes pH as lactobacillus growth is metabolically active in cold

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Reduces biofilms via 3 mechanisms for faster cure and low recurrence

Why take a pill?

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Achieving Where Others Fail

Initial studies support high human effectiveness!

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The Science

Microbiology confirms mechanisms of action.

  • Eradicates infection

  • Stops Inflammation & Symptoms

  • Promotes pH/healthy microbiome

  • Destroys biofilms

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Animal Studies

  • Two Mouse Studies

  • Confirm 2 Mechanisms of Action and Effectiveness p=0.0002 and p=0.0033

  • Existing drugs failed mouse model!

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First-in-Human Studies

  • Two Human Clinical Trials

  • 11 out of 11 Cures for VVC* alone, VVC/BV, BV**

  • Results confirm both Symptom Relief and Cure

  • 2 Mechanisms of Action proven

  • 19 Additional Cures

VVC* is Vulvovaginal Candidiasis

BV** is Bacterial Vaginosis

Vlisse™ is a Class I Device in the European Union CE Mark Pending and a FDA Class II device pending FDA clearance.

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