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VLISSE
Controlled-Cooling Device
Vlisse™ is a prescription, drug-free medical device designed to treat vaginal yeast and bacterial infections using patented controlled-cooling technology. Developed by a board-certified OB/GYN, Vlisse introduces a non-pharmaceutical approach that addresses infection and inflammation without the drugs, hormones, or chemicals commonly used in current treatments.
Faster Treatment
Effective Treatment*
*The Journal of Infectious Diseases, Use of Intravaginal Cooling to Provide Symptom Relief in Women With Vulvovaginal Candidiasis and Reduce Immunopathology in an Accompanying Mouse Model
Immediate Symptom Relief
Drug Free, No Chemicals
How Vlisse Works!
Four Mechanisms of Action
*Cures the Infection by returning the hyphae (infection) back to dormant-bud state; kills fungus: confirmed in 2 cases; kills bacteria: confirmed in 4 cases
Stops inflammation/symptoms of itching, pain, and swelling
Normalizes pH as lactobacillus growth is metabolically active in cold
Reduces biofilms via 3 mechanisms for faster cure and low recurrence
Achieving Where Others Fail
Initial studies support high human effectiveness!
The Science
Microbiology confirms mechanisms of action.
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Eradicates infection
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Stops Inflammation & Symptoms
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Promotes pH/healthy microbiome
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Destroys biofilms
Animal Studies
Two Mouse Studies
Confirm 2 Mechanisms of Action and Effectiveness p=0.0002 and p=0.0033
Existing drugs failed mouse model!
First-in-Human Studies
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Two Human Clinical Trials
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11 out of 11 Cures for VVC* alone, VVC/BV, BV**
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Results confirm both Symptom Relief and Cure
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2 Mechanisms of Action proven
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19 Additional Cures
VVC* is Vulvovaginal Candidiasis
BV** is Bacterial Vaginosis